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Clarivein Endovenous Vein
Clarivein Varicose Vein Procedure

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Patients with symptomatic varicose veins and venous insufficiency can now be treated with a painless and FDA approved endovenous technique known as Clarivein.   Symptomatic varicose veins refers to individuals who have varicose veins and associated symptoms including pain, discomfort, itching, burning, cramping, throbbing, and restless legs.  Venous insufficiency is a medical problem that is associated with veins that don't work as well as they once did in youth. If you are having problems with varicose veins, consider the Clarivein procedure:


Clarivein EVLT  Clarivein EVLT Los Angeles


Clarivein is a new and innovative endovenous therapy for the treatment of venous reflux and venous insufficiency in patients who have symptomatic vein problems.  The procedure was developed using an alternative therapeutic modality compared to old fashioned vein stripping techniques.  The benefits of Clarivein stem from its ability to mechanically ablate and sclerotherapy ablate the diseased vein.


A study by Djalali et al from the University of Zurich evaluated studies examining the efficacy of endovenous ablation and venous insufficiency.  The study detailed the increasing influence of endovenous vein ablation as a useful and predictable treatment for patients with venous insufficiency.  Whereas vein stripping was the gold standard for the treatment of vein stripping, the high success rates achieved with endovenous ablation have made it possible for the endovenous technique to surpass vein stripping as the method of choice in vein treatment. 


In the last decade, enormous strides have been made to treat unwanted varicose veins with less invasive procedures when compared to old fashioned vein stripping.  These new procedures utilize a technique known as endovenous ablation, of which the treatments VNUS, Venefit, and EVLT have been FDA approved for. Endovenous ablation is a non-surgical option for venous reflux that targets the defective veins and vein valves that contribute to venous insufficiency and venous reflux.  The treatments incorporate an efficient and painless way to seal off and collapse defective veins that are harming the normal circulatory network. The benefits of Clarivein include its high level of efficacy, reduction in intraprocedural pain and discomfort, minimal recovery, and decreased incidence of ancillary tissue damage.  Results from long term studies have shown a 95% success rate at the one year period, which is comparable to other endovenous systems. 




If you are suffering from varicose veins, you are among millions of healthy adult males and females who may be suffering from a condition known as chronic venous insufficiency.  Many patients report symptoms associated with venous insufficiency in addition to having bulging varicose veins.  If you have any of the following problems, the symptoms may be an early warning sign of a more serious medical vein problem that will require attention:


  1. LEG EDEMA:Venous insufficiency may impair your normal circulatory system, leading to venous hypertension and venous edema.  Leg swelling may be caused by a number of different medical issues, with vein disease being among the most common.  Ultrasound examination may help elucidate the cause of your leg and ankle swelling.  During your vein consultation in our Los Angeles vein clinic, we can help provide you with surgical and non-surgical options for venous-related leg swelling.  Clarivein procedures can help improve leg edema in those patients with longstanding venous reflux and venous insufficiency. 
  2. SKIN CHANGES: Skin changes include leg discoloration and a gradual sclerosis or thickening/scarring of the skin on the ankles and legs.  Venous eczema and venous lipodermatosclerosis may lead to irreversible changes in your skin.  Early intervention is key in reversing some of the skin changes associated with venous insufficiency. 
  3. VENOUS ULCERS:No one wants to hear about the risk of venous ulcers, but there are finite risks to developing a chronic venous ulcer if you have longstanding vein disease.  Venous ulcers typically show up on the medial ankle and can take years to improve in appearance.  Clarivein procedures are ideal for those patients with venous insufficiency and venous ulcers. 
  4. BULGING VARICOSE VEINS: Bulging varicose veins can occur as a result of venous hypertension, venous reflux, or incompetent perforator veins.  The goal of our vein consultations is to help elucidate the causes of your varicose vein issues and to help control them at their root.  If you have bulging varicose veins and have not seen improvement in the size and caliber of your veins, you may be a candidate for endovenous vein treatment such as EVLT, Venefit, VNUS, and Clarivein.
  5. BLEEDING VARICOSE VEINS: Varicose veins sometimes rupture spontaneously or as a result of trauma or injury to the skin.  Often, the high pressure in a varicose vein may make it vulnerable to extended bleeding.  If you have experienced a bleeding varicose vein, you will attest to the fact that they bleed extensively and quite profusely.  Patients who have a bleeding varicose vein should elevate the leg, apply pressure, and seek the care of an experienced vein surgeon or physician. 




  1. What is vein disease? Veins are one-way blood vessels that play an important role in our circulatory system as they return blood from the hands and feet back to our hearts.  The one-way flow of blood works with the help of vein valves within the veins.  If these vein valves begin to age, they begin to cause poor blood flow in the veins.  This represents a condition known as reflux.  In our Los Angeles vein clinic, we begin each consultation by determining whether you have cosmetic spider veins or a more medical vein problem known as venous reflux.  If you have venous reflux, then we can recommend new procedures to treat this condition such as Clarivein, EVLT, Venefit, and VNUS. 
  2. What are some risk factors for vein disease? There are many known and unknown risk factors for vein disease, including a family history of varicose veins, a personal history of vein ulcers, recurrent varicose and spider veins, frequent lifting of heavy weights, previous pregnancies, hormonal exposure, and standing or sitting for extended periods of time. 
  3. Is the Clarivein procedure performed in your Los Angeles vein clinic FDA approved? The FDA approved the Clarivein procedure as a medical treatment for venous reflux and venous insufficiency. For more information about the Santa Monica Vein Center and Varicose Veins, you may visit our website at 
  4. Do I need a physician referral to schedule an appointment for Clarivein? If you have vein problems, including bulging varicose veins, leg pain, discomfort, leg swelling, leg edema, and leg cramping; you may be a candidate for the Clarivein system.  Our office works closely with primary care physicians and internists in the management of varicose veins and venous disease.  Our office can expedite your request for consultation and treatment, if necessary. 
  5. Will insurance pay for the cost of spider vein treatment? Spider vein treatment is generally considered a cosmetic procedure.  Although...more research is showing that spider veins may actually be associated with venous reflux.  The goal of spider vein treatment is to treat the root cause of the spider veins prior to treating the spider veins themselves.  Insurance may cover the cost of treatment for venous insufficiency, but does not typically cover the cost of sclerotherapy for spider veins. 
  6. If I have undergone Unna Boot therapy for a venous stasis ulcer, can Clarivein help? Venous stasis ulcers may have underlying venous reflux and varicose veins.  If you have a venous stasis ulcer and need treatment that is beyond local wound care, our office will help diagnose whether you have underlying venous reflux and help you then determine if Clarivein endovenous ablation may help your condition. 
  7. How long does the Clarivein endovenous vein treatment take to perform? The Clarivein procedure uses a combination of mechanical and sclerosant-based technology to ablate unwanted root sources of venous reflux.  Much like the VNUS and EVLT procedures, Clarivein procedures take less than one-half hour to perform and require no general anesthesia.  Clarivein procedures require a small amount of local anesthetic injected into the skin immediately before endovenous treatment. 
  8. Does your vein clinic also offer EVLT and Venefit procedures? Our office is a comprehensive vein clinic located in Los Angeles.  We offere medical and cosmetic treatment of small spider veins, reticular veins, and abnormal varicose veins.  Dr. Raffy Karamanoukian is a board certified vein surgeon and an expert in venous disease.  He offers both the EVLT and Venefit procedures on an outpatient basis for the elimination of venous reflux. 
  9. What are some options for endovenous treatment as opposed to Clarivein? Endovenous ablation can treat venous reflux and venous insufficiency at the saphenofemoral junction.  Treatments have evolved from traditional vein stripping to newer endovenous techniques to treat venous reflux.  The alternatives to Clarivein procedure include the Venefit procedure, VNUS procedure, and EVLT endovenous laser ablation.  Dr. Karamanoukian can explain the differences between these varicose vein and venous treatments during your consultation in Los Angeles. 
  10. Is there a risk of thermal injury with the Clarivein procedure? There are many different types of endovenous ablation, including radiofrequency ablation and laser ablation.  The benefits of the Clarivein procedure evolves from the source of venous ablation, which is mechanical and sclero based in Clarivein, as opposed to laser or radiofrequency.  
  11. How can the CEAP Classification help me in vein treatment? The CEAP Classification allows doctors to objectify the diagnosis and categorization of vein disease.  It is not a treatment algorithm, but rather a way for doctors to communicate about the severity of vein disease in a particular individual. 
  12. Where are venous stasis ulcers usually found on the body? Most venous stasis ulcers are found in the medial ankle and medial leg.  Patients who have unilateral vein disease or vein reflux will likely have the venous stasis ulcer on the affected side. Patients may also have leg discoloration as a result of lipodermatosclerosis.  
  13. Is the Clarivein endovenous vein treatment painful? Most patients who undergo the Clarivein procedure are pleased to note that Clarivein is well tolerated with minimal pain or discomfort.  The target of Clarivein is the Greater Saphenous Vein. We would recommend that you take two Tylenol tablets (if you have no allergies to Tylenol) prior to your procedure. 
  14. How long is recovery with Clarivein procedures? There is very little recovery time with the Clarivein procedure.  Most patients are able to return to normal activities the day of the procedure, including work.  Patients are advised to return to work the following day with very little in terms of post-Clarivein restrictions? 
  15. Is Clarivein FDA approved? Clarivein has been used abroad with a high level of safety and efficacy in vein treatment.  Clarivein is now FDA approved for the treatment of venous reflux in patients with venous insufficiency. 
  16. Do you have an office in New York? If you live in the New York or Ontario Canada areas, please visit for information about the Clarivein treatment in the Upstate New York area. 
  17. Will my insurance pay for the Clarivein treatment? Clarivein is performed to treat medical vein problems. Insurance reimbursement depends on your individual carrier and insurance policy.  In our Los Angeles vein clinic, we have found that insurance does cover Clarivein and other endovenous procedures, provided you have the right insurance, you have documented medical vein disease, and you have complied with pretreatment conservative measures.  Insurance will not cover cosmetic vein treatments.



CEAP Classification System:


How do physicians and vein experts know how bad your varicose vein problems are? The most straightforward and practical way is to scale your symptoms and problems on the CEAP chart in order to determine how unhealthy your veins are.  The CEAP chart was designed to provide an objective assessment tool for varicose veins and venous disease.



C0 no signs of vein disease
C1 telangiectasias, spider veins, reticular veins, thread veins
C2 bulging varicose veins
C3 edema and leg swelling as a result of vein disease 
C4 changes in the skin as a result of venous insufficiency
C5 healed venous ulcer
C6 active venous ulcer



Venous stasis ulcers are chronic wounds that form on the medial or inner leg and ankle area as a result of poor venous circulation.  Patients tend to ignore these wounds until they become enlarged and fail to heal normally.  A venous stasis ulcer is also referred to as a leg ulcer and can be a serious health problem if ignored.  Although there are many reasons to develop leg ulcers, venous reflux and venous insufficiency remain top reasons because vein disease is so prevalent.  If you are experiencing leg ulcers or are concerned that the skin changes in your legs may develop into leg ulcers, there may be some vein related questions you would like answered.  During your consultation in our Los Angeles vein clinic, you will be asked basic questions about your vein history and family history of veins. Further, a vein mapping procedure and ultrasound examination may also be performed to evaluate the extent of vein disease.  If you have underlying vein reflux, a procedure known as Clarivein, EVLT, or Venefit may be one early option for care.  Endovenous ablation and local wound care may help solve your leg ulcer problems.  

A very unlikely, but possible complication of longstanding venous insufficiency was reported by a group at the University Hospital Center in Zagreb Department of Dermatology and Venerealogy ( Ceovic R, et al.) which described a patient with a therapeutic challenge: namely, development of diffuse basal cell carcinoma in the setting of bilateral venous insufficiency and stasis dermatitis.  It is believed that chronically inflamed skin processes may increase the likelihood of metaplasia or cancerous development.  Although this is a rare complication, our center has witnessed this disease process in our Los Angeles vein clinic.  Our center provides expertise in vein management and can help you solve complex vein problems in a regimented and expert fashion.




Endovenous laser ablation for varicose veins in Los Angeles: Endovenous laser ablation has dramatically revolutionized the treatment of bulging varicose veins, venous ulcers, and varicose vein problems.  Many years ago, the only option available for varicose veins was a surgery known as vein stripping.  Now, using endovenous technique, Dr. Karamanoukian can identify the root source of your varicose vein problems and vein valves problem and directly eliminate venous reflux using a state of the art laser.  The benefit of this endovenous laser is that it requires minimal recovery and minimal downtime after the procedure.  Most patients tolerate the endovenous laser treatment under local anesthesia and require no significant painkillers after the procedure.  Endovenous laser ablation is known as EVLT or VenaCure and has a long safety record for permanent results with varicose vein treatments.  If you have questions regarding varicose veins endovenous laser and wish to schedule a consultation or second opinion consultation in the Los Angles area, please call 310-998-5535.


varicose vein clarivein los angeles


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